Polymers scale new heights

Hsp90 reaches new heights

Introduction Hsp90 (heat-shock protein 90) is an abundant molecular chaperone, but its function seems to be restricted to the folding of proteins involved in cell signalling, such as transcription factors and protein kinases. This restricted set of ‘clients’ (see Fig. 1) makes Hsp90 an attractive target for cancer therapeutics. As an anti-Hsp90 drug is now in clinical trials, the meeting was re...

Do tall trees scale physiological heights?

D oes genotypic variation in leaf form and function among tree species reflect adult height or only the seedling regeneration niche? For trees in closed canopy forests, typical adult tree height directly indicates the position of the species in the light hierarchy of the canopy. However, it is unknown whether trees that characteristically differ in mature height have similar or different canopy...

Peripheral blood stem cells reach new heights.

Indian Banking-Scaling New Heights in Emerging New Competition

Indian banking industry has transformed in recent years due to the globalization market which has resulted in fierce competition. This new competitive environment has resulted in new challenges for the Indian banks especially for public sector banks to retain their share. The present paper is mainly concerned with the analysis of factors that influence the performance of banks. The paper examin...

Multi-Scale Simulation of Hyperbranched Polymers

In a previous work, we described a multi-scale protocol for the simulation of the conformation and dynamics of macromolecules that was applied to dendrimer molecules proving its predictive capability by comparison with experimental data. That scheme is now employed in order to predict conformational properties (radius of gyration) and overall hydrodynamic properties (translational diffusion and...